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Blog
At Drug Science we like to cover different topics relating to drugs. These topics cover the many different ways that psychoactive substances have an impact on our culture and society.
![Drug development in psychiatry: 50 years of failure and how to resuscitate it](https://static.wixstatic.com/media/2cee5a_747c05219b3046a2a7f95c1991345590~mv2.png/v1/fill/w_305,h_172,fp_0.50_0.50,q_95,enc_auto/2cee5a_747c05219b3046a2a7f95c1991345590~mv2.webp)
David Nutt
4 days ago1 min read
Drug development in psychiatry: 50 years of failure and how to resuscitate it
The past 50 years have seen remarkable advances in the science of medicine. The pharmacological treatments of disorders such as hypertension
![](https://static.wixstatic.com/media/2cee5a_f9b071ad13c84b9e9785f82ce803b6d7~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/2cee5a_f9b071ad13c84b9e9785f82ce803b6d7~mv2.webp)
![The Australia story: Current status and future challenges for the clinical applications of psychedelics](https://static.wixstatic.com/media/2cee5a_f9b071ad13c84b9e9785f82ce803b6d7~mv2.jpg/v1/fill/w_306,h_172,fp_0.50_0.50,q_90,enc_auto/2cee5a_f9b071ad13c84b9e9785f82ce803b6d7~mv2.webp)
David J Nutt, Peter Hunt, Anne Katrin Schlag and Paul Fitzgerald
Dec 18, 20241 min read
The Australia story: Current status and future challenges for the clinical applications of psychedelics
The past decade has seen a huge increase in clinical research with psychedelic drugs and 3,4-methylenedioxymethamphetamine (MDMA)
![](https://static.wixstatic.com/media/2cee5a_282582d82629458da4c56d1c288eaf5b~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/2cee5a_282582d82629458da4c56d1c288eaf5b~mv2.webp)
![Medical cannabis could save NHS £4 billion each year](https://static.wixstatic.com/media/2cee5a_282582d82629458da4c56d1c288eaf5b~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/2cee5a_282582d82629458da4c56d1c288eaf5b~mv2.webp)
Medical cannabis could save NHS £4 billion each year
Allowing medical cannabis to be prescribed on the NHS for chronic pain could save the state healthcare provider almost £4 billion annually,
![Suicidal Ideation in Medicinal Cannabis Patients: A 12-Month Prospective Study](https://static.wixstatic.com/media/2cee5a_7ffe308b0c834a54bb34508f74c950fb~mv2.png/v1/fill/w_305,h_172,fp_0.50_0.50,q_95,enc_auto/2cee5a_7ffe308b0c834a54bb34508f74c950fb~mv2.webp)
James Bunn
Jul 31, 20242 min read
Suicidal Ideation in Medicinal Cannabis Patients: A 12-Month Prospective Study
To document the prevalence and correlates of suicidal ideation (SI) among individuals seeking cannabis-based medicinal products (CBMPs); to
![Prescribed Medical Cannabis Use Among Older Individuals: Patient Characteristics and Improvements in Well‑Being: Findings from T21](https://static.wixstatic.com/media/2cee5a_7f2910e7683045f2ba543e76dce7e70b~mv2.png/v1/fill/w_306,h_172,fp_0.50_0.50,q_95,enc_auto/2cee5a_7f2910e7683045f2ba543e76dce7e70b~mv2.webp)
Michael Lynskey
Jun 17, 20242 min read
Prescribed Medical Cannabis Use Among Older Individuals: Patient Characteristics and Improvements in Well‑Being: Findings from T21
There are important differences between individuals aged 65+ years and younger individuals receiving cannabis-based medicinal products. Olde
![Prescribed Medicinal Cannabis for the Treatment of Chronic Pain Comorbid with Depression: Real World Evidence from Project Twenty21](https://static.wixstatic.com/media/2cee5a_676fe20be2ff432382a5c32ea05d892c~mv2.png/v1/fill/w_305,h_172,fp_0.50_0.50,q_95,enc_auto/2cee5a_676fe20be2ff432382a5c32ea05d892c~mv2.webp)
Alkyoni Anthanasiou-Fragkouli
Jun 6, 20242 min read
Prescribed Medicinal Cannabis for the Treatment of Chronic Pain Comorbid with Depression: Real World Evidence from Project Twenty21
Chronic pain is one of the most common conditions for which people seek treatment with cannabis-based medicinal products (CBMPs) and there i
![](https://static.wixstatic.com/media/6d80b2_c9f33460037947b29411674a9b9c2da0~mv2.webp/v1/fill/w_250,h_250,al_c,q_30,blur_30,enc_auto/6d80b2_c9f33460037947b29411674a9b9c2da0~mv2.webp)
![Medicinal cannabis for treating PTSD and comorbid depression: Real World Evidence from Project T21](https://static.wixstatic.com/media/6d80b2_c9f33460037947b29411674a9b9c2da0~mv2.webp/v1/fill/w_305,h_172,al_c,q_90,enc_auto/6d80b2_c9f33460037947b29411674a9b9c2da0~mv2.webp)
Dr Anne Schlag, Professor David Nutt and more
Mar 12, 20241 min read
Medicinal cannabis for treating PTSD and comorbid depression: Real World Evidence from Project T21
Authors Michael Lynskey, Alkyoni Athanasiou-Fragkouli, Hannah Thurgur, Anne Schlag and David Nutt Published March 12, 2024 Background...
![](https://static.wixstatic.com/media/6d80b2_66677214acc14db9adba373da62b1879~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_66677214acc14db9adba373da62b1879~mv2.webp)
![Cannabis-based medicinal products for the treatment of Long COVID symptoms: current and potential applications](https://static.wixstatic.com/media/6d80b2_66677214acc14db9adba373da62b1879~mv2.jpg/v1/fill/w_306,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_66677214acc14db9adba373da62b1879~mv2.webp)
Dr Hannah Thurgur, Dr Anne Schlag, and more
Aug 31, 20231 min read
Cannabis-based medicinal products for the treatment of Long COVID symptoms: current and potential applications
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can result in a range of persistent symptoms impacting everyday funct
![](https://static.wixstatic.com/media/6d80b2_e13f3aca986a4b66b5cef9470a3a5a43~mv2.webp/v1/fill/w_250,h_250,al_c,q_30,blur_30,enc_auto/6d80b2_e13f3aca986a4b66b5cef9470a3a5a43~mv2.webp)
![A drug harms ranking study for Aotearoa New Zealand](https://static.wixstatic.com/media/6d80b2_e13f3aca986a4b66b5cef9470a3a5a43~mv2.webp/v1/fill/w_305,h_172,al_c,q_90,enc_auto/6d80b2_e13f3aca986a4b66b5cef9470a3a5a43~mv2.webp)
Dr Rose Crossin
Aug 21, 20237 min read
A drug harms ranking study for Aotearoa New Zealand
Drug harm is a significant public health burden in Aotearoa New Zealand ; though harms are not evenly distributed across the populati
![](https://static.wixstatic.com/media/6d80b2_b9b9cd1eaa5148a180aea5105f8c1758~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_b9b9cd1eaa5148a180aea5105f8c1758~mv2.webp)
![Bayesian analysis of real-world data as evidence for drug approval: Remembering Sir Michael Rawlins](https://static.wixstatic.com/media/6d80b2_b9b9cd1eaa5148a180aea5105f8c1758~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_b9b9cd1eaa5148a180aea5105f8c1758~mv2.webp)
Balázs Szigeti, Professor David Nutt and more
Jul 17, 20231 min read
Bayesian analysis of real-world data as evidence for drug approval: Remembering Sir Michael Rawlins
The two pillars of modern medical research are where in most randomized controlled trials (RCTs), the active treatment is compared with plac
![](https://static.wixstatic.com/media/6d80b2_ef3b81c25bf647aa86a270def2d92233~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_ef3b81c25bf647aa86a270def2d92233~mv2.webp)
![Psychedelic therapy in the treatment of addiction: the past, present and future](https://static.wixstatic.com/media/6d80b2_ef3b81c25bf647aa86a270def2d92233~mv2.jpg/v1/fill/w_306,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_ef3b81c25bf647aa86a270def2d92233~mv2.webp)
Rayyan Zafar, Maxim Siegel and more
Jun 12, 20231 min read
Psychedelic therapy in the treatment of addiction: the past, present and future
Psychedelic therapy has witnessed a resurgence in interest in the last decade from the scientific and medical communities with evidence now
![Preliminary findings from T21 Australia](https://static.wixstatic.com/media/6d80b2_39783c81b86a411a8779b757465de321~mv2.png/v1/fill/w_305,h_172,fp_0.50_0.50,q_95,enc_auto/6d80b2_39783c81b86a411a8779b757465de321~mv2.webp)
Kylie O’Brien, Justin Beilby and more
Mar 23, 20232 min read
Preliminary findings from T21 Australia
An observational study of patients prescribed medicinal Cannabis for chronic pain, anxiety, posttraumatic stress disorder and multiple...
![](https://static.wixstatic.com/media/6d80b2_492f5b1a20d5476cad7cda2f00215c09~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_492f5b1a20d5476cad7cda2f00215c09~mv2.webp)
![The value of real world evidence: The case of medical cannabis](https://static.wixstatic.com/media/6d80b2_492f5b1a20d5476cad7cda2f00215c09~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_492f5b1a20d5476cad7cda2f00215c09~mv2.webp)
Professor Michael Lynskey, Dr Anne Schlag and more
Nov 3, 20224 min read
The value of real world evidence: The case of medical cannabis
Authors Anne Katrin Schlag, Rayyan Zafar, Michael Lynskey, Lawrence D Phillips, Alkyoni Athanasiou-Fragkouli, David J Nutt Published...
![](https://static.wixstatic.com/media/6d80b2_b6d9e93b89ec4cbca227bf0a8c811c1c~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_b6d9e93b89ec4cbca227bf0a8c811c1c~mv2.webp)
![User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study](https://static.wixstatic.com/media/6d80b2_b6d9e93b89ec4cbca227bf0a8c811c1c~mv2.jpg/v1/fill/w_306,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_b6d9e93b89ec4cbca227bf0a8c811c1c~mv2.webp)
Robin Carhart-Harris and Professor David Nutt
Jul 7, 202232 min read
User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study
Authors Robin Carhart-Harris, David Nutt Published July 30, 2010 Abstract This study used a web-based questionnaire to investigate user...
![](https://static.wixstatic.com/media/6d80b2_4f1e5a61bb64467a9719c4ecb9ed56e2~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_4f1e5a61bb64467a9719c4ecb9ed56e2~mv2.webp)
![Cannabinoids and the endocannabinoid system in fibromyalgia: a review of preclinical and clinical research](https://static.wixstatic.com/media/6d80b2_4f1e5a61bb64467a9719c4ecb9ed56e2~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_4f1e5a61bb64467a9719c4ecb9ed56e2~mv2.webp)
Dr Anne Schlag, Professor David Nutt and more
Jun 21, 20222 min read
Cannabinoids and the endocannabinoid system in fibromyalgia: a review of preclinical and clinical research
Authors Stephanie Bourke, Anne Schlag, Saoirse Elizabeth O’Sullivan, David Nutt, David Finn Published May 21, 2022 Fibromyalgia affects...
![](https://static.wixstatic.com/media/6d80b2_723b1c59a6ff465d8ae4b71e248b92ef~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_723b1c59a6ff465d8ae4b71e248b92ef~mv2.webp)
![Characteristics of People Seeking Prescribed Cannabinoids for the Treatment of Chronic Pain: Evidence From Project Twenty 21](https://static.wixstatic.com/media/6d80b2_723b1c59a6ff465d8ae4b71e248b92ef~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_723b1c59a6ff465d8ae4b71e248b92ef~mv2.webp)
Dr Anne Schlag, Professor David Nutt and more
Jun 13, 20223 min read
Characteristics of People Seeking Prescribed Cannabinoids for the Treatment of Chronic Pain: Evidence From Project Twenty 21
Authors Anne Katrin Schlag, Michael Lynskey, Alan Fayaz, Alkyoni Athanasiou-Fragkouli, Brigitta Brandner, Barbara Haja, Elizabeth Iveson...
![](https://static.wixstatic.com/media/6d80b2_637f2f3daeac476789dd7776edbefc73~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_637f2f3daeac476789dd7776edbefc73~mv2.webp)
![The UK's first unsanctioned overdose prevention site; A proof-of-concept evaluation](https://static.wixstatic.com/media/6d80b2_637f2f3daeac476789dd7776edbefc73~mv2.jpg/v1/fill/w_306,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_637f2f3daeac476789dd7776edbefc73~mv2.webp)
Gillian Shorter, Magdalena Harris and more
May 6, 20221 min read
The UK's first unsanctioned overdose prevention site; A proof-of-concept evaluation
Authors Gillian W Shorter, Magdalena Harris, Andrew McAuley, Kirsten MA Trayner, Alex Stevens Published May 4, 2022 Background The United...
![](https://static.wixstatic.com/media/6d80b2_684d0ee1504a448da4db9fad8a194093~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_684d0ee1504a448da4db9fad8a194093~mv2.webp)
![Are psychedelics dangerous? - What the research says](https://static.wixstatic.com/media/6d80b2_684d0ee1504a448da4db9fad8a194093~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_684d0ee1504a448da4db9fad8a194093~mv2.webp)
Dr Anne Schlag, Professor David Nutt and more
Feb 3, 20223 min read
Are psychedelics dangerous? - What the research says
Authors Anne K Schlag, Jacob Aday, Iram Salam, Jo C Neill, David J Nutt Published February 3, 2022 Psychedelic medicines are a rapidly...
![](https://static.wixstatic.com/media/6d80b2_078e70f6bd274db38dde99162caa2309~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_078e70f6bd274db38dde99162caa2309~mv2.webp)
![Medical cannabis for severe treatment resistant epilepsy in children: a case series of 10 patients](https://static.wixstatic.com/media/6d80b2_078e70f6bd274db38dde99162caa2309~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_078e70f6bd274db38dde99162caa2309~mv2.webp)
Dr Anne Schlag, Professor David Nutt and more
Dec 15, 20212 min read
Medical cannabis for severe treatment resistant epilepsy in children: a case series of 10 patients
Authors Rayyan Zafar, Anne Schlag, Lawrence Phillips, David J Nutt Published December 15, 2021 We previously reported on the legalisation...
![](https://static.wixstatic.com/media/6d80b2_89f90da8a1184165a51c9b3a2f737e1b~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_89f90da8a1184165a51c9b3a2f737e1b~mv2.webp)
![Controversies in Medical Cannabis](https://static.wixstatic.com/media/6d80b2_89f90da8a1184165a51c9b3a2f737e1b~mv2.jpg/v1/fill/w_306,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_89f90da8a1184165a51c9b3a2f737e1b~mv2.webp)
Dr Anne Schlag, Professor David Nutt and more
May 18, 20212 min read
Controversies in Medical Cannabis
Authors Anne Katrin Schlag, Saoirse E. O’Sullivan, Rayyan R. Zafar, David J.Nutt Published May 18, 2021 Knowledge about the therapeutic...
![](https://static.wixstatic.com/media/6d80b2_18e20cf994c44ac195af77a15c767ec3~mv2.jpg/v1/fill/w_250,h_250,fp_0.50_0.50,q_30,blur_30,enc_auto/6d80b2_18e20cf994c44ac195af77a15c767ec3~mv2.webp)
![Psychedelic Microdosing - Just a Placebo Effect?](https://static.wixstatic.com/media/6d80b2_18e20cf994c44ac195af77a15c767ec3~mv2.jpg/v1/fill/w_305,h_172,fp_0.50_0.50,q_90,enc_auto/6d80b2_18e20cf994c44ac195af77a15c767ec3~mv2.webp)
Balázs Szigeti, Professor David Nutt and more
Mar 2, 20212 min read
Psychedelic Microdosing - Just a Placebo Effect?
Authors: Balázs Szigeti, Laura Kartner, Allan Blemings, Fernando Rosas, Amanda Feilding, David J. Nutt, Robin L. Carhart-Harris, David...
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